Category Archives: Medical MCQS

Psychiatry Mcqs 2

1. Re: NICE guidelines on depression
  1. Mild depression antidepressants (ADs) are the first line treatment
  2. Dysthymia antidepressants are effective
  3. Antidepressants are recommended for moderate to severe depression
  4. In severe depression antidepressants or CBT is recommended
  5. Patient with one episode of depression with functional impairment should receive prophylaxis for 2 years
2. NICE guidelines on treatment resistant depression
  1. Combination of antidepressants are supported
  2. Augmentation with lithium is not useful
  3. ECT is recommended
  4. Augmentation with antipsychotic is recommended
3. Re: Treatment of depression
  1. People with depression are at increased risk of cardiovascular disease
  2. 2/3rd of patient who have a single episode of depression will go on to have another episode of depression
  3. Dose for prophylaxis – Adults should receive the same dose as used for acute treatment
  4. Lithium also has some efficacy in the prophylaxis of unipolar depression
  5. Patients with more than two episodes are recommended 2 years prophylactic treatment
4. Re: Treatment of depression
  1. Poor response at 2 weeks predicts no response in the future for that drug
  2. If there is poor tolerability switching between drug classes is a good option
  3. If there is non-response switching to another drug in the same class will not have any effect
  4. A single episode of depression has be treated for at least 6-9 months after full remission
  5. 50% of patients will relapse if treatment is discontinued on remission

5. True/False

  1. Relapse rates after ECT is lesser than after ADs
  2. In the elderly a lower dose of AD may be used in prophylaxis than what was used in acute treatment
  3. Each episode of depression increases the chances of having another episode
  4. Schizophrenia increases the possibility of having depression

Answers                                                                                                        

1. Re: NICE guidelines on depression
  1. Mild depression antidepressants (ADs) are the first line treatment – F, Not recommended, active monitoring, individual guided self help, CBT, exercise
  2. Dysthymia antidepressants are effective – T
  3. Antidepressants are recommended for moderate to severe depression – T, first line – SSRI
  4. In severe depression antidepressants or CBT is recommended – F, ADs and CBT is recommended
  5. Patient with one episode of depression with functional impairment should receive prophylaxis for 2 years – F, if the patient had 2 episodes 2 years are recommended
2. NICE guidelines on treatment resistant depression
  1. Combination of antidepressants are supported – T
  2. Augmentation with lithium is not useful – F, useful recommended
  3. ECT is recommended – T
  4. Augmentation with antipsychotic is recommended – T
3. Re: Treatment of depression
  1. People with depression are at increased risk of cardiovascular disease – T
  2. 2/3rd of patient who have a single episode of depression will go on to have another episode of depression – T
  3. Dose for prophylaxis – Adults should receive the same dose as used for acute treatment – T, in the elderly the dose may be reduced
  4. Lithium also has some efficacy in the prophylaxis of unipolar depression – T, but should not be used as a single agent. May be used in combination with a AD
  5. Patients with more than two episodes are recommended 2 years prophylactic treatment – T
4. Re: Treatment of depression
  1. Poor response at 2 weeks predicts no response in the future for that drug – T, Taylor et al, 2006, meta analysis
  2. If there is poor tolerability switching between drug classes is a good option – T, but not much evidence
  3. If there is non-response switching to another drug in the same class will not have any effect – F, some evidence
  4. A single episode of depression has be treated for at least 6-9 months after full remission – T
  5. 50% of patients will relapse if treatment is discontinued on remission – T, within 3-6 months

5. True/False

  1. Relapse rates after ECT is lesser than after ADs – F, Similar, thus need prophylaxis with ADs
  2. In the elderly a lower dose of AD may be used in prophylaxis than what was used in acute treatment – T, but not recommended for adults
  3. Each episode of depression increases the chances of having another episode – T, through kindling
  4. Schizophrenia increases the possibility of having depression – T, all non-affective illness increase possibility

Psychiatry Mcqs 1

1. True or False Re: APs in schizophrenia
  1. The response to APs vary greatly between individuals
  2. There is no first choice AP for all
  3. SGAs are not superior to FGAs
  4. When non-clozapine SGAs are compared to each other Olanzapine is superior
  5. Risperidone is superior to other SGAs except olnz. and cloz.
2. When compared with FGAs the following SGAs have proven more efficacious
  1. Olanzapine
  2. Ziprazidone
  3. Aripiprazole
  4. Risperidone
  5. Amisulpride
3. True or false Re: APs in schizophrenia
  1. Depot preparations are associated with better global outcome and reduction in the frequency of hospital admission
  2. GASS and LUNSERS are questionnaires used to detect drug side effects in pts. on APs
  3. Following Depot administration it would take close 6-12 week reach a steady plasma concentration
  4. AP polypharmacy can cause sudden death
4. True of False Re: Neuroleptic equivalent doses
  1. Closely follows the drugs efficacy
  2. Related the maximum dose that can be prescribed
  3. Related to chlorpromazine equivalents
  4. Based on dopamine studies
  5. Only has value in FGAs
5. True of False Re: Maximum licensed doses
  1. Chlorpromazine – 1000 mg/day
  2. Haloperidol – 30 mg/day
  3. Clozapine 900mg/day
  4. Olanzapine 20mg/day
  5. Risperidone – 24mg/day

Answers                                 

1. True or False Re: APs in schizophrenia
  1. The response to APs vary greatly between individuals – T
  2. There is no first choice AP for all – T, due to above reason
  3. SGAs are not superior to FGAs – T, After reviewing the CATIE and CUTLES studies the world psychiatric association made this statement
  4. When non-clozapine SGAs are compared to each other Olanzapine is superior – T, Leucht et al 2009 Meta analysis, head-to-head comparison of SGAs
  5. Risperidone is superior to other SGAs except olnz. and cloz. – T, Leucht et al 2009 Meta analysis, head-to-head comparison of SGAs
2. When compared with FGAs the following SGAs have proven more efficacious
  1. Olanzapine – T
  2. Ziprazidone – F
  3. Aripiprazole – F
  4. Risperidone – T
  5. Amisulpride – T
3. True or false Re: APs in schizophrenia
  1. Depot preparations are associated with better global outcome and reduction in the frequency of hospital admission – T, Schooler (2003)
  2. GASS and LUNSERS are questionnaires used to detect drug side effects in pts. on APs – T, Glasgow Antipsychotic Side-Effect Scale (GASS) And the Liverpool University Neuroleptic Side-Effect Ratings Scale (LUNSERS), can be a useful first step in this process.
  3. Following Depot administration it would take close 6-12 week reach a steady plasma concentration – T
  4. AP polypharmacy can cause sudden death – T
4. True of False Re: Neuroleptic equivalent doses
  1. Closely follows the drugs efficacy – F, not related
  2. Related the maximum dose that can be prescribed – F, not related
  3. Related to chlorpromazine equivalents – T
  4. Based on dopamine studies – T, also clinical experience and guess work
  5. Only has value in FGAs – ?T, not useful for SGA
5. True of False Re: Re: maximum licensed doses
  1. Chlorpromazine – 1000 mg/day – T
  2. Haloperidol – 30 mg/day – T
  3. Clozapine 900mg/day – T
  4. Olanzapine 20mg/day – T
  5. Risperidone – 24mg/day – F, 16mg/day
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Medical MCQ 7

in a child with bilateral lens dislocation . mild joint stiffness and learning disability the most likely diagnosis is which of the followings 
1. strickler syndrome 
2. marfan syndrome 
3. Ehler -Danlos syndrome 
4 .homocystinuria 
5. benign familial joint hypermobility

see answer 

Anatomy question 2

Pain in posterior 1/3rd of tongue after
tonsillectomy indicates injury of :
A. VII nerve
B. IX nerve
C. V nerve
D. XII nerve

 

 

 

 

Answer is B. IX nerve

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